Selected publications


We have collated articles relevant to CROWN and COS development.

About the CROWN initiative

Core Outcome Sets in Women’s and Newborn Health: A Systematic Review
Duffy JMN, Rolph R, Gale C, et al. (2017) BJOG; doi: 10.1111/1471-0528.14694

Reducing research waste in benign gynaecology and fertility research
Duffy JMN, Bhattacharya S, Herman M et al. on behalf of the Cochrane Gynaecology and Fertility Group (2017) BJOG, 124:366–369.

The CROWN Initiative: journal editors invite researchers to develop core outcomes in women’s health
Khan KS (2014) BJOG; 121: 1181-1182

Core Outcomes for Clinical Trials: Moving Ahead
Rowe T (2013J Obstet Gynaecol Can; 35(10):877–878

Core outcome sets

A core outcome set for studies evaluating the effectiveness of prepregnancy care for women with pregestational diabetes
Egan AM, Galjaard S, Maresh MJA, et al. (2017) Diabetologia; doi: 10.1007/s00125-017-4277-4

Development of a core outcome set for epilepsy in pregnancy (E-CORE): a national multi-stakeholder modified Delphi consensus study
Al Wattar BH, Tamilselvan K, Khan KS et al. (2016) BJOG; 124 (4): 661–667

A Core Outcome Set for Evaluation of Interventions to Prevent Preterm Birth (available also in Dutch and Chinese)
van ‘t Hooft J, Duffy JMN; Daly M, et al. on behalf of the Global Obstetrics Network (GONet)(2016Obstetrics & Gynecology; 127(1): 49–58

Evaluating Maternity Care: A Core Set of Outcome Measures
Devane D, Begley CM, Clarke M, et al. (2007) Birth; 34(2): 164–172


Standardizing Abortion Research Outcomes (STAR): a protocol for developing, disseminating, and implementing a core outcome set for medical and surgical abortion
Whitehouse KC, Kim CR, Ganatra B, et al. (2017) Contraception, doi: 10.1016/j.contraception.2016.12.009

Protocol for the development of a core outcome set for autologous fat grafting to the breast
Agha RA, Fowler AJ, Pidgeon TE, et al. on behalf of the VOGUE Steering Group (2016) Int J Surg., 7;31:104–6

Protocol for developing, disseminating and implementing a core outcome set for endometriosis
Hirsch M, Duffy JMN, Barker C et al. On behalf of iHOME Collaboration (2016

A protocol for developing, disseminating and implementing a core outcome set for pre-eclampsia.
Duffy JMN, van’t Hooft J, Gale C, et al. (2016Pregnancy Hypertens; doi:

A core outcome set for neonatal abstinence syndrome: study protocol for a systematic review, parent interviews, and a Delphi survey
Kelly LE, Jansson LM, Moulsdale W, et al. (2016) Trials, 17(1):536

Development of a core outcome set for use in determining the overall success of gastroschisis treatment.
Allin B, Ross A, Marven S, et al. (2016) Trials, 17(1):360

Effectiveness of prepregnancy, care for women with pregestational diabetes mellitus: protocol for a systematic review of the literature
and identification of a core outcome set using a Delphi survey
Egan AM, Smith V, Devane D, et al. (2015) Trials, 16(1):356

Development of a core outcome set for research and audit studies in reconstructive breast surgery
Potter S, Holcombe C, Ward JA, et al. (2015) The British jJournal of Surgery, 102(11):1360-71

Core Outcome Set – methods and commentaries

The COMET Handbook
Williamson PR, Altman DG, Bagley H et al. (2017) Trials; 18(Suppl 3):280

A Call to Action for Data Definition Standardization and Core Outcome Sets
Dildy GA (2017) BJOG, doi: 10.1111/1471-0528.14729

P-hacking can be avoided with core outcome sets: preterm birth research is ready to take this leap
van ‘t Hooft J, Khan KS (2017) BJOG, 124 (7):  1017

Improving core outcome set development: qualitative interviews with developers provided pointers to inform guidance
Gargon E, Williamson PR, Young B (2017) J Clin Epidem, doi: 10.1016/j.jclinepi.2017.04.024

Validating Evidence and Using Standard Outcomes for Recurrent Pregnancy Loss Tests and Treatments
Scott J (2016) Clin Obst & Gyn, 59 (3): 524–534

Core Outcome Set–STAndards for Reporting: The COS-STAR Statement
Kirkham JJ, Gorst S, Altman DG et al. (2016) PLoS Med 13(10)

Influence of methodology upon the identification of potential core outcomes. Recommendations for core outcome set developers are needed
Duffy JMN, McManus RJ. (2016) BJOG, doi: 10.1111/1471-0528.14219

Developing core outcome sets for clinical trials: issues to consider
Williamson P, Altman D, Blazeby J, et al. (2012) Trials, 13:132

Delphi Technique to Determine Which Outcomes to Measure in Clinical Trials: Recommendations for the Future Based on a Systematic Review of Existing Studies
Sinha I, Rosalind S and Williamson P (2011) PLoS Med, 8(1): e1000393

The COMET (Core Outcome Measures in Effectiveness Trials) Initiative
Williamson P, Altman D, Blazeby J et al. (2011) Trials, 12 (Suppl 1): A70

For more guidance and information on the methodology of developing core outcome set go here.