Projects without external funding or awaiting funding
|Health problem||Full title||Description||COMET registration number||Status|
|Breast cancer||Validated Outcomes in the Grafting of Fat to the Breast (VOGUE)||The objective is to develop a core outcome set (COS) for AFG to the breast. Study protocol is available here||860||Ongoing|
|Cardiovascular Disease||Primary endpoints in cohort studies evaluating cardiovascular disease risk after reproductive disorders||The study aims to systematically review relevant CVD endpoints used in prognostic research among women with reproductive disorders and to develop a core outcome set.||701||Ongoing|
|Cardiovascular Disease||Developing a core outcome set for pregnant women with cardiac disease||Trials and cohort studies evaluating therapeutic interventions in women with cardiac disease report many different outcomes resulting in significant outcome reporting bias and an inability to compare results across studies. The development and use of core outcome sets would help to address these issues.||834||Ongoing|
|Gestational diabetes mellitus||Developing a core outcome set for clinical trials in Gestational diabetes mellitus||To develop a COS for use in studies on screening, prevention and treatment of GDM.||686||Planning|
|Hyperemesis gravidarum||Development of a definition and core outcome set for studies in hyperemesis gravidarum||The aim is to develop a consensus definition of hyperemesis gravidarum and core outcome set for use in future trials, systematic reviews and guidelines on the management of the condition.||805||Ongoing|
|Immune thrombocytopenic purpura||Constructing a core outcome set for Immune Thrombocytopenia in Pregnancy||The objective of this project is to generate a core outcome set for studies focusing on the evolution and management of Immune thrombocytopenic purpura in pregnancy.||840||Planning|
|Induction of Labour||Development of a Core Outcome Set for trials on Induction of Labour (COSIOL)||The objectives are:|
a) to identify all relevant obstetric, fetal and neonatal outcomes in randomised studies of IOL; b) to develop a set of core outcomes for reporting on IOL using the Delphi technique.
You can learn more about the project here.
|Intrauterine death/ stillbirth||Defining a core outcome set for bereavement care interventions following intrauterine death, stillbirth and neonatal loss - International Collaboration for Harmonising Outcomes for Stillbirth (iCHOOSE)||We aim to define a core outcome set for bereavement care interventions following intrauterine death, stillbirth and neonatal loss, that is evidence-based, relevant and appropriate for patients and researchers alike.||775||Planning|
|Iron Deficiency Anaemia||Constructing a core outcome set for Iron Deficiency Anaemia in Pregnancy (IDeA)||The objective of this project is to produce a core outcome set for studies focusing on the identification, assessment and management of iron deficiency anaemia in pregnancy and postpartum.||836||Ongoing|
|Maternity care||Developing a core outcome set for caesarean delivery maternal infectious outcomes||Objective: to review all Cochrane Reviews and contributing trials in the area to devise a common core outcome set to propose to the CROWN initiative for use in any newly published clinical trials.||763||Ongoing|
|Menopause||Core outcome set in Menopause (COMMA)||The aim of this project is to develop, disseminate, and implement a core outcome set for menopause engaging with key stakeholders, including healthcare professionals, researchers, and women who have experienced the menopause transition||917||Ongoing|
|Multiple pregnancies||Developing a core outcome set for research in multiple pregnancies||The aim is to develop a core outcome set for research in multiple pregnancies, irrespective of chorionicity.||844||Planning|
|Neonatal Abstinence Syndrome||A core outcome set for neonatal abstinence syndrome (NAS)||The NAS core outcome set is a first step in facilitating high-quality evidence that will ease the comparability between studies and foster meta-analysis. The synthesis of NAS effectiveness evidence informs clinical decision making, improves health outcomes and saves resources||808||Ongoing|
|Obstetric Anal Sphincter Injury||The CO-OPT Study: Core Outcomes in Obstetric Anal Sphincter Injury Prevention and Treatment||The objective of this project is to develop a core outcome set for studies evaluating interventions for the prevention and treatment of Obstetric Anal Sphincter Injuries (OASIS).||959||Planning|
|Pelvic floor disorders||Developing a core outcome set for female pelvic floor disorders||Objectives:|
Produce, disseminate, and implement core outcome sets for female pelvic floor disorders, including urinary incontinence, pelvic organ prolapse, childbirth perineal trauma, and pelvic pain syndromes.
|Reduced fetal movements/ Stillbirth||Developing a core outcome set for clinical trials on interventions for the detection and management of reduced fetal movements in pregnancy||The aim is to develop a core outcome set for use in future trials on the topic of reduced fetal movements in pregnancy.||928||Planning|
|Venous thromboembolism||Constructing a core outcome set for Venous Thromboembolism in Pregnancy||The objective of this project is to produce a core outcome set for studies focusing on the identification, assessment and management of VTE in pregnancy.||839||Ongoing|
|Vulval skin disorders||Core outcome sets for Clinical trials and Observational Studies in Vulvovaginal Disease||The aims of this project are to determine a COS to be used in trials for the treatment of vulvovaginal conditions that are acceptable to the research, clinical community and patients internationally. This initiative will cover a spectrum of at least three large disease categories in the field of genital disease: 1) vulvovaginal pain, 2) vulval inflammatory dermatoses, and 3) vulvovaginal infections.||999||Planning|