Ongoing Core Outcome Sets

Projects without external funding or awaiting funding

Health problemFull titleDescriptionCOMET registration numberStatus
Breast cancerValidated Outcomes in the Grafting of Fat to the Breast (VOGUE)The objective is to develop a core outcome set (COS) for AFG to the breast. Study protocol is available here860Ongoing
Cardiovascular DiseasePrimary endpoints in cohort studies evaluating cardiovascular disease risk after reproductive disordersThe study aims to systematically review relevant CVD endpoints used in prognostic research among women with reproductive disorders and to develop a core outcome set.701Ongoing
Cardiovascular DiseaseDeveloping a core outcome set for pregnant women with cardiac diseaseTrials and cohort studies evaluating therapeutic interventions in women with cardiac disease report many different outcomes resulting in significant outcome reporting bias and an inability to compare results across studies. The development and use of core outcome sets would help to address these issues.834Ongoing
Gestational diabetes mellitusDeveloping a core outcome set for clinical trials in Gestational diabetes mellitusTo develop a COS for use in studies on screening, prevention and treatment of GDM.686Planning
Hyperemesis gravidarumDevelopment of a definition and core outcome set for studies in hyperemesis gravidarumThe aim is to develop a consensus definition of hyperemesis gravidarum and core outcome set for use in future trials, systematic reviews and guidelines on the management of the condition.805Ongoing
Immune thrombocytopenic purpuraConstructing a core outcome set for Immune Thrombocytopenia in PregnancyThe objective of this project is to generate a core outcome set for studies focusing on the evolution and management of Immune thrombocytopenic purpura in pregnancy. 840Planning
Induction of LabourDevelopment of a Core Outcome Set for trials on Induction of Labour (COSIOL)
COSIOL
The objectives are:
a) to identify all relevant obstetric, fetal and neonatal outcomes in randomised studies of IOL; b) to develop a set of core outcomes for reporting on IOL using the Delphi technique.
You can learn more about the project here.
695Ongoing
Iron Deficiency AnaemiaConstructing a core outcome set for Iron Deficiency Anaemia in Pregnancy (IDeA)
The objective of this project is to produce a core outcome set for studies focusing on the identification, assessment and management of iron deficiency anaemia in pregnancy and postpartum.836Ongoing
Maternity careDeveloping a core outcome set for caesarean delivery maternal infectious outcomesObjective: to review all Cochrane Reviews and contributing trials in the area to devise a common core outcome set to propose to the CROWN initiative for use in any newly published clinical trials.763Ongoing
MenopauseCore outcome set in Menopause (COMMA)
The aim of this project is to develop, disseminate, and implement a core outcome set for menopause engaging with key stakeholders, including healthcare professionals, researchers, and women who have experienced the menopause transition917Ongoing
Multiple pregnanciesDeveloping a core outcome set for research in multiple pregnanciesThe aim is to develop a core outcome set for research in multiple pregnancies, irrespective of chorionicity.844Planning
Neonatal Abstinence SyndromeA core outcome set for neonatal abstinence syndrome (NAS)The NAS core outcome set is a first step in facilitating high-quality evidence that will ease the comparability between studies and foster meta-analysis. The synthesis of NAS effectiveness evidence informs clinical decision making, improves health outcomes and saves resources808Ongoing
Obstetric Anal Sphincter InjuryThe CO-OPT Study: Core Outcomes in Obstetric Anal Sphincter Injury Prevention and Treatment
The objective of this project is to develop a core outcome set for studies evaluating interventions for the prevention and treatment of Obstetric Anal Sphincter Injuries (OASIS).959Planning
Pelvic floor disordersDeveloping a core outcome set for female pelvic floor disorders Objectives:
Produce, disseminate, and implement core outcome sets for female pelvic floor disorders, including urinary incontinence, pelvic organ prolapse, childbirth perineal trauma, and pelvic pain syndromes.
981Ongoing
Reduced fetal movements/ StillbirthDeveloping a core outcome set for clinical trials on interventions for the detection and management of reduced fetal movements in pregnancyThe aim is to develop a core outcome set for use in future trials on the topic of reduced fetal movements in pregnancy.928Planning
Venous thromboembolism Constructing a core outcome set for Venous Thromboembolism in PregnancyThe objective of this project is to produce a core outcome set for studies focusing on the identification, assessment and management of VTE in pregnancy.839Ongoing
Vulval skin disordersCore outcome sets for Clinical trials and Observational Studies in Vulvovaginal DiseaseThe aims of this project are to determine a COS to be used in trials for the treatment of vulvovaginal conditions that are acceptable to the research, clinical community and patients internationally. This initiative will cover a spectrum of at least three large disease categories in the field of genital disease: 1) vulvovaginal pain, 2) vulval inflammatory dermatoses, and 3) vulvovaginal infections.999Planning