Category: Core Outcome Set

A systematic review of core outcome sets in women’s and newborn health

By Louisa Waite BJOG  has recently published a systematic review, which evaluates the progress of the CROWN initiative and the development of core outcome sets for women’s and newborn health. It found that 49 core outcome sets have been registered,

Posted in Core Outcome Set, Uncategorized

First steps in development of core outcome set – ethical approval

By Natalie Cooper A key element of a core outcome set (COS) is patient and public involvement; after all, it is patients and their families who struggle and suffer from an illness, so who better to help us identify which

Posted in Core Outcome Set, Gynaecology, Researcher Perspective

Core Outcome Set for Hirschsprung’s Disease – The NETS1HD Study

By Benjamin Allin Edited by Ewelina Rogozińska Hirschsprung’s disease affects approximately 300-350 children in the UK each year and is caused by the failure of development of the nerves within the intestines. Affected children require an operation to remove part

Posted in Core Outcome Set, Researcher Perspective

A winding road to funding – story of a core outcome set for endometriosis trials

By Dr Martin Hirsch I was fresh faced and green behind the ears when I first heard about core outcome sets in 2013. Fast forward three years and I have been on a journey getting this, the first core outcome

Posted in Core Outcome Set, Endometriosis, Gynaecology, Researcher Perspective

Core outcomes in women’s health, a road map to better research

By Bassel H. Al Wattar Edited by Ewelina Rogozińska The last two decades have witnessed a major shift towards evidence-based medicine in clinical practice. Aiming to benefit patients and improve health outcomes, our investment in clinical research and its applicability

Posted in Core Outcome Set, Epilepsy in pregnancy, Researcher Perspective

Why I got involved in a core outcome set project? – researcher’s perspective

By Janneke van’t Hooft Edited by Ewelina Rogozińska Some questions require such large sample sizes that they cannot be answered unless primary data from multiple studies are combined. One example of such a situation is the use of preventive treatment

Posted in Core Outcome Set, preterm birth, Researcher Perspective

First steps towards core outcomes in obstetrics

by Janneke van’t Hooft There is a widespread, unwarranted variation in reporting of outcomes in evaluation research.(1) As heterogeneity in outcomes and their measurements slows down the process of evidence synthesis and uptake, there  now seems to be a mounting

Posted in Core Outcome Set, preterm birth

Updates from CROWN

by Janneke van’t Hooft and Zinah Sorefan                         Did you know?

Posted in Core Outcome Set, Get Involved, preterm birth

Defining Core Outcomes for studies on the prevention of Preterm Birth

Zinah Sorefan Zinah Sorefan, CROWN Project Coordinator. First Core Outcome Set (COS) endorsed by CROWN published in Obstetrics and Gynaecology. Randomised clinical trials (RCTs) and systematic reviews have to measure endpoints that are relevant and meaningful to patients, clinicians, and

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BMA Award for Improving Clinical Outcomes for Cervical Cancer

Zinah Sorefan Zinah Sorefan, CROWN Project Coordinator. BMA Research Grant Awards Winner 2015: The Strutt & Harper grant for research into improving clinical outcome measures Dr Natalie Cooper MBChB MRCOG PHD and Professor Khalid Khan MBBS MRCOG MSc MMEd, Queen

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